That’s actually useful information and narrows it down a lot.
If InDesign freezes even with a brand new blank document, then we can probably stop looking at the document itself.
The part that stands out most is this:
InDesign isn’t creating anything under AppData → Roaming → Adobe or AppData → Local → Adobe.
For the AppData check, don’t browse to the folder manually
Open File Explorer, click the address bar at the top, paste this and press Enter:
%APPDATA%\Adobe
Then do the same with:
%LOCALAPPDATA%\Adobe
That makes sure Windows takes you to the AppData folders for the user account you’re actually logged into.
Once you’re there, check whether there are any InDesign folders inside. Also try creating a simple test folder there manually.
If you can’t create a folder in either location, or Windows gives an access/permission warning, then that would support the idea that InDesign can’t write its preference/cache folders properly.
Uninstalling and reinstalling the app does not repair a damaged Windows user profile or unblock AppData access.
Check Event Viewer
After InDesign freezes, check:
Event Viewer > Windows Logs > Application
Look for errors around the time of the freeze involving InDesign.exe, Adobe, permissions, .NET, fonts, or application hangs.