From personal experience, I think cold calling is a very effective sales method for designs – if it’s done right. It sounds like you’ve taken the first step in that you’ve identified a list of potential clients. Good for you. The next step is to get a contact name within each company so you know who to reach out to. Here’s the big thing – send the contact something ahead of time. Get creative with this. Make a poster and send it to them in a tube. Make a book and FedEx it to the person. (Side note: yes, FedEx is expensive, but if you have a highly targeted list and really want to stand out, FedEx is a great way to do so.) Bottom line is two fold. First, who isn’t going to open a package? Secondly, it get’s your name in front of the person before you call – so your cold call is more of a warm call. “Hi, this is Anthonyo. I sent you a work sample earlier this week, and I wanted to follow up…” Cold calling is not fun, and you’ll experience some rudeness but I’ve gotten several new clients over the years by calling people.